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Cade Cunningham and Jalen Duren scored 29 points apiece for the Pistons, while the NBA's Most Valuable Player Shai Gilgeous-Alexander missed a ninth straight game for the Thunder because of injury.
The Pistons improved to 43-14, going ahead of the Thunder for the league's best record and extending their lead the top of the Eastern Conference above the Boston Celtics, who lost 103-84 at the Denver Nuggets.
Nikola Jokic scored 30 points and grabbed 12 rebounds for the Nuggets.
The Milwaukee Bucks overcame the continued absence of two-time MVP Giannis Antetokounmpo with a calf injury to win 118-116 at home against the Cleveland Cavaliers.
The Cavs were without new signing James Harden after he suffered a broken thumb in Tuesday's win over the New York Knicks.
The Houston Rockets beat the Sacramento Kings 128-97 - their biggest victory of the season - while the Golden State Warriors won 133-112 at the Memphis Grizzlies.

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